De Quervain’s is pain on the thumb side of the wrist, about where a watch would rest. It is associated with movement of the wrist or thumb. You will normally notice the pain when you lift up a baby, reach out to grab something with an open thumb or lift the thumb up and down repeatedly. You can also notice pain in positions where your wrist is bent forward and towards the little finger side of your hand. Side-to-side movement of the wrist is another common movement that will cause symptoms. The pain will be even worse if you are holding something heavy or doing something requiring force.